FIELD: organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention relates to novel derivatives of methylene-bis-phosphonic acid anhydride of the formula (I) 
where Y1, Y2, Y3, Y4 mean the group 
or OP(O)R2(OR3) where R1, R2, R3 mean hydrogen atom, C1-22-alkyl, possibly substituted aryl or SiR3 where R3 means C1-C4-alkyl under condition that one of groups Y1, Y2, Y3, Y4 is another than group OR1 or NR2R3; Q1 and Q2 mean hydrogen, fluorine, chlorine, bromine, iodine atoms. Invention relates also to method for preparing these novel compounds and pharmaceutical preparations containing these novel compounds. Compounds exhibit the more controlling effect on the body metabolism and functions. EFFECT: improved preparing method, valuable medicinal properties. 11 cl, 5 tbl, 13 ex
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