FIELD: organic chemistry. SUBSTANCE: product: new bis-pilocarpates of the general formula (I) where (A): Y - hydrogen or acyl-group (II) and W - group -O-A-O-Z-$$$ where $$$ - hydrogen or acyl-group (III); groups R and $$$ have different values and can be similar or distinct; A - aliphatic or aromatic bridge-group, and -Z-$$$ - (IV); or (B): W - OR where R has value as indicated above; Y is (V) where $$$ has a value as indicated above; B means the same as A and $$$ is (VI) or (C) W and Y together mean -A-O-Z-C-B-C- where symbols have the same values as above. The synthesized compounds are used in medicine for glaucoma treatment. EFFECT: improved method of synthesis. 7 cl
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Authors
Dates
1997-12-27—Published
1993-05-28—Filed