FIELD: medicine. SUBSTANCE: method involves immunizing experimental animals with wooping cough vaccine pretreated with low frequency ultrasound (40- 50 kHz). The mice are decapitated one day later. Histamine quantity is determined in brain tissue. Its amount being equal to 22.4 mcg/g and higher, marked wooping cough vaccine toxicity is considered to be the case. EFFECT: accelerated and simplified method. 2 tbl
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