FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention relates to substituted phenylalkenoylguanidines and their pharmaceutically acceptable salts and physiologically functional derivatives. Invention describes compounds of the formula (Ia):
wherein T1 and T2 mean independently:
or hydrogen atom, and T1 and T2 can't represent hydrogen atom simultaneously; L-z means:
wherein L means -C≡C-, -NH-CH2-CH2-O-; R(E) means hydrogen atom, (C1-C4)-alkyl; R(1), R(2) mean hydrogen, fluorine, chlorine atom, CN, -SO2-CH3, -(C1-C4)-alkyl, -O-(C1-C4)-alkyl and their physiologically acceptable salts, physiologically derivatives and method for their preparing. These compounds can be used, for example, as medicinal agents for prophylaxis and treatment of cholelithiasis disease.
EFFECT: valuable medicinal properties of compounds.
4 cl, 7 ex
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