FIELD: chemistry.
SUBSTANCE: described is a 15β-substituted oestradio derivative having selective oestrogenic activity. The preferred compound is 7α-ethyl-15β-methyl-19-nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17β-diol.
EFFECT: obtaining compounds which can be used in treating or preventing diseases or physiological conditions related to oestrogen receptors.
11 cl, 4 ex, 2 tbl
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STEROID COMPOUNDS, METHOD FOR SELECTIVE MODIFICATION, PHARMACEUTICAL COMPOSITION | 2001 |
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COMPOUNDS, SET, ANDROGENIC COMPOSITION | 2000 |
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15,15-DIALKYLSTEROID COMPOUNDS AND METHOD OF PREPARATION THEREOF | 1994 |
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PROGESTERONE RECEPTOR MODULATORS | 2005 |
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NONAROMATIC ESTROGENIC STEROID, PHARMACEUTICAL COMPOSITION | 2000 |
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BRIDGE-CONTAINING ESTRATRIENES | 1990 |
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RU2087479C1 |
METHOD OF SYNTHESIS OF SULFATIZED ESTROGEN MIXTURE | 1998 |
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RU2184741C2 |
18-METHYL-19-NORANDROST-4-ENE-17,17-SPIROETHER (18-METHYL-19-NOR-20-SPIROX-4-EN-3-ON) AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUND | 2007 |
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SULFAMATE DERIVATIVES, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS | 1996 |
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RU2159774C2 |
DERIVATIVES OF 11,21-BISPHENYL-19-NORPREGNANE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING | 1995 |
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RU2152952C2 |
Authors
Dates
2010-04-20—Published
2005-09-05—Filed