FIELD: medicine, infectious diseases.
SUBSTANCE: invention relates to antigenic composition and a method for detection of antibodies raised to Treponema pallidum in syphilis diagnosis. The antigenic composition comprises synthetic cardiolipin and synthetic lecithin (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine) and can comprise additionally cholesterol and alcohol. The antigenic composition can be used as an immunoreagent in immune analysis for detection of antibodies associated with the T. pallidum infection. The proposed method shows the enhanced sensitivity and specificity with respect to the T. pallidum infection.
EFFECT: improved detecting method.
23 cl, 8 tbl, 7 ex
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