MEANS OF NONSPECIFIC SERODIAGNOSIS OF SYPHILIS SERONEGATIVE FORMS Russian patent published in 2012 - IPC A61B10/00 A61K39/02 A61P43/00 G01N33/53 

FIELD: medicine.

SUBSTANCE: invention refers to venereology and can be used for nonspecific serodiagnosis of syphilis seronegative forms. This requires the identification of nonspecific (anticardiolipin) antibodies by means of nonspecific serological reaction to syphilis. In case of no response to serological reactions the highly specific antigen of cultural pale treponemas are inserted into the body beforehead. Then after a certain period of time set for the syphilitic infection activation the anticardiolipin antibodies are identified. If the anticardiolipin antibodies are identified syphilis is diagnozed.

EFFECT: means provides the improvement of the accuracy of nonspecific serodiagnosis of syphilis seronegative forms due to the activation of the syphilis process as a result of inserted highly specific antibody of cultural pale treponemas which allows changing the course of seronegative syphilis that is characterized by no immune reply to the syphilis activator to the seropositive form that is characterized by the immune reply to the activator.

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