FIELD: biotechnology, microbiology, vitamins.
SUBSTANCE: method relates to a method for preparing riboflavin by culturing the microorganism Bacillus subtilis as a producer in the nutrient medium containing rib-operon from Bacillus amyloliquefaciens, or microorganism able for utilization of glycerophosphate as a single carbon source, or eliciting the resistance against inhibition of growth by glyoxylate, and extraction of riboflavin prepared. Invention uses the following strains as producers of riboflavin: B. subtilis GM51/pMX45, B. subtilis GM41/pMX45, B. subtilis GM44/pMX45. Invention provides preparing riboflavin of the high degree of effectiveness.
EFFECT: improved preparing method.
5 cl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR MICROBIOLOGIAL SYNTHESIS OF PURINE NUCLEOSIDE OF 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE RIBOSIDE (AICAR) AND BACILLUS SUBTILIS STRAIN - PRODUCER OF AICAR | 2008 |
|
RU2405833C2 |
| STRAIN OF BACILLUS SUBTILIS - A PRODUCER OF RIBOFLAVIN (VARIANTS) | 1994 |
|
RU2081175C1 |
| BACTERIA Bacillus subtilis PRODUCING 5`-AMINOIMIDAZOLE-4-CARBOXAMIDERIBOSIDE (AICAR), AND METHOD OF MICROBIOLOGICAL SYNTHESIS OF AICAR BY CULTURING THIS BACTERIUM | 2013 |
|
RU2542387C1 |
| STRAIN OF BACTERIUM BACILLUS SUBTILIS - A PRODUCER OF RIBOFLAVIN | 1994 |
|
RU2081906C1 |
| METHOD OF PRODUCING PURINE RIBONUCLEOSIDE AND RIBONUCLEOTIDES | 2008 |
|
RU2422510C2 |
| METHOD OF PURINE NUCLEOZIDES AND NUCLEOTIDES PRODUCTION BY FERMENTATION WITH APPLICATION OF BACTERIA BELONGING TO GENUS Escherichia OR Bacillus | 2006 |
|
RU2365622C2 |
| YdhL PROTEIN FROM Bacillus amyloliquefaciens, DNA FRAGMENT, BACTERIUM BELONGING TO GENUS Esherichia OR Bacillus AS PRODUCER OF PURINE NUCLEOSIDES, METHOD FOR PRODUCTION OF PURINE NUCLEOSIDES AND PURINE NUCLEOTIDES | 2005 |
|
RU2294962C2 |
| MUTANT PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE, DNA CODING SAID SYNTHETASE, BACTERIUM CODING SAID DNA, METHOD OF PRODUCING PURINE NUCLEOSIDES AND METHOD OF PRODUCING PURINE NUCELOTIDES | 2008 |
|
RU2403286C2 |
| METHOD FOR PREPARING L-AMINO ACID BY FERMENTATION METHOD, STRAIN OF BACTERIUM ESCHERICHIA COLI AS PRODUCER OF L-AMINO ACID (VARIANTS) | 1999 |
|
RU2207376C2 |
| MICROORGANISM FOR PRODUCING SIMULTANEOUSLY L-AMINO ACID AND RIBOFLAVIN AND METHOD FOR PRODUCTION OF L-AMINO ACID AND RIBOFLAVIN USING SAID METHOD | 2012 |
|
RU2588657C2 |
