FIELD: veterinary virology and biotechnology.
SUBSTANCE: invention relates to rotavirus strain having high biological, antigenic, and immune activity, as well as dominated properties in relation to epizootic isolates. Claimed virus strain is reproduced in single-layer passed cell cultures wherein after incubation for 24-48 h it accumulates in titer of 5.5-7.5 lg TCD30/cm3. (TCD - tissue cytopathogenic dose). Strain of present invention holds basic biological properties when passing in cell culture.
EFFECT: strain with increased biological, antigenic, and immune activity, inactivation resistance and dominated properties in relation to epizootic isolates.
12 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SORBED INACTIVATED VACCINE AGAINST CATTLE ROTAVIRAL INFECTION | 2005 |
|
RU2302258C1 |
| ASSOCIATED INACTIVATED EMULSION BOVINE VIRAL DIARRHOEA, ROTAVIRUS AND CORONAVIRUS INFECTIONS VACCINE | 2012 |
|
RU2515058C1 |
| COMBINED EMULSION INACTIVATED VACCINE AGAINST ROTAVIRAL AND CORONAVIRAL CATTLE INFECTIONS | 2008 |
|
RU2366458C1 |
| STRAIN ROTAVIRUS "TE87" OF SEROTYPE G8P7 IN CATTLE FOR PREPARING DIAGNOSTIC PREPARATION | 2003 |
|
RU2258738C1 |
| EMULSION INACTIVATED ASSOCIATED VACCINE AGAINST CATTLE REDNOSE AND CORONOVIRAL INFECTION | 2007 |
|
RU2378017C2 |
| EMULSION INACTIVATED ASSOCIATED VACCINE AGAINST CATTLE PARAGRIPPE-3, REDNOSE AND CORONOVIRAL INFECTION | 2007 |
|
RU2378014C2 |
| STRAIN "VNIIZZH 2003" OF GOAT-POX VIRUS VARIOLA VIRUS CAPRINUM TO PRODUCE BIOPREPARATIONS FOR DIAGNOSTICS AND SPECIFIC PROPHYLACTICS OF GOAT-POX | 2008 |
|
RU2389791C1 |
| NADL-ARRIAH VIRUS STRAIN OF BOVINE VIRAL DIARRHOEA FOR MAKING BIOPREPARATIONS FOR DIAGNOSIS, SPECIFIC PREVENTION AND TREATMENT OF BOVINE VIRAL DIARRHOEA | 2010 |
|
RU2449013C2 |
| INACTIVATED EMULSION ASSOCIATED VACCINE FOR CATTLE PARAINFLUENZA-3, INFECTIOUS RHINOTRACHEITIS AND VIRAL DIARRHOEA | 2012 |
|
RU2504400C1 |
| STRAIN "VNIIZZH" OF CATTLE CORONAVIRUS FOR PREPARING DIAGNOSTIC, VACCINE AND CURATIVE PREPARATIONS | 2004 |
|
RU2268937C1 |
