FIELD: genetic and cellular engineering, veterinary science and animal husbandry.
SUBSTANCE: invention proposes a capsule for implantation in animal representing a semi-penetrating membrane made of alginate-poly-L-lysine-alginate wherein rat myoblast cells are included (L6). These cells secrete porcine somatostatin owing to the expression cassette incorporated into cells consisting of a nucleotide sequence encoding the insulin secretory signal and a nucleotide sequence encoding active form of porcine somatostatin operatively associated with its. Invention provides the development of the safety and highly technological method for provides animal with necessary amount of the growth hormone involving intramuscular administration of one or more capsules in the pig neck region or ear base.
EFFECT: improved administration method, valuable properties of capsule.
4 cl, 13 dwg, 3 tbl, 3 ex
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