FIELD: biotechnology.
SUBSTANCE: device for insulin secretion containing a population of non-native pancreatic β-cells, and non-native pancreatic β-cells demonstrate an in vitro response consisting of glucose-stimulated insulin secretion to glucose stimulation. Moreover, the device contains a semi-permeable membrane, which is designed to retain non-native pancreatic β-cells in the device and ensure the passage of insulin secreted by non-native pancreatic β-cells.
EFFECT: invention can be effectively used in cell therapy.
18 cl, 17 dwg, 5 tbl
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