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(19)

(11)

2 271 355

(13)

(51)

IPC

C07D277/28(2006-01-01)

A61K31/426(2006-01-01)

A61P25/00(2006-01-01)

(21) (22)

Application

2002112227/15, 2000-10-10

(24)

Start date

2000-10-10

(22)

Actual filing date

2000-10-10

(45)

Published

2006-03-10

(72)

Inventor

Shabrie De Lasson'Er P'Er-Eht'EnnKharnett DzheremiaBigg DenniPomm'E ZhakLannua ZhakLiberator Ann-MariTjur'O Kristof

(73)

Holder

Sos'Ete De Konsej De Reshersh Eh D`Applikas'On S'Entifik

DERIVATIVES OF FIVE-MEMBERED HETEROCYCLES, METHOD FOR THEIR PREPARING AND THEIR USING AS MEDICINES Russian patent published in 2006 - IPC C07D277/28 A61K31/426 A61P25/00

Abstract RU 2271355 C2

FIELD: organic chemistry, medicine, pharmacology, pharmacy.

SUBSTANCE: invention relates to a new compound, i. e. to 4-[2-(aminomethyl)-1,3-thiazole-4-yl]-2,6-di-(tert.-butyl)phenol and a pharmaceutical composition used for inhibition of lipid peroxidation and/or as a modulating agent of sodium channels and a medicinal agent comprising this compound. Invention provides the enhanced effectiveness of inhibition of lipid peroxidation and modulation of sodium channels activity.

EFFECT: improved preparing method, valuable medicinal properties of agents and composition.

22 cl, 349 ex

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RU 2 271 355 C2

Authors

Shabrie De Lasson'Er P'Er-Eht'Enn

Kharnett Dzheremia

Bigg Denni

Pomm'E Zhak

Lannua Zhak

Liberator Ann-Mari

Tjur'O Kristof

Dates

2006-03-10—Published

2000-10-10—Filed