DERIVATIVES OF FIVE-MEMBERED HETEROCYCLES, METHOD FOR THEIR PREPARING AND THEIR USING AS MEDICINES Russian patent published in 2006 - IPC C07D277/28 A61K31/426 A61P25/00 

Abstract RU 2271355 C2

FIELD: organic chemistry, medicine, pharmacology, pharmacy.

SUBSTANCE: invention relates to a new compound, i. e. to 4-[2-(aminomethyl)-1,3-thiazole-4-yl]-2,6-di-(tert.-butyl)phenol and a pharmaceutical composition used for inhibition of lipid peroxidation and/or as a modulating agent of sodium channels and a medicinal agent comprising this compound. Invention provides the enhanced effectiveness of inhibition of lipid peroxidation and modulation of sodium channels activity.

EFFECT: improved preparing method, valuable medicinal properties of agents and composition.

22 cl, 349 ex

Similar patents RU2271355C2

Title Year Author Number
DERIVATIVES OF FIVE-MEMBER HETEROCYCLES, METHOD OF PRODUCTION AND USE THEREOF AS MEDICINAL AGENTS 2000
  • Shabrie De Lasson'Er P'Er-Eht'Enn
  • Kharnett Dzheremia
  • Bigg Denni
  • Pomm'E Zhak
  • Lannua Zhak
  • Liberator Ann-Mari
  • Tjur'O Kristof
RU2380362C2
FIVE-MEROUS HETEROCYCLE DERIVATIVES, METHOD FOR PREPARING AND USING THEM AS THERAPEUTIC AGENTS 2009
  • Shabrie De Lasson'Er P'Er-Eht'Enn
  • Kharnett Dzheremia
  • Bigg Denni
  • Pomm'E Zhak
  • Lannua Zhak
  • Liberator Ann-Mari
  • Tjur'O Kristof
RU2530882C2
NEW DERIVATIVES OF AMIDINES, THEIR PREPARING AND USING AS MEDICINAL AGENTS 2000
  • Shabrie De Lasson'Er P'Er-Eht'Enn
  • Kharnett Dzheremia
RU2272807C2
DERIVATIVES OF FIVE-MEMBERED HETEROCYCLES, THEIR PREPARING AND USING AS MEDICINAL AGENTS 2002
  • Kharnett Dzheremia
  • Bigg Denni
  • Liberator Ann-Mari
  • Rollan Alen
RU2288224C2
MODULATORS OF SODIUM CHANNELS REPRESENTING DERIVATIVES OF 2-PIPERIDYLIMIDAZOLES 2001
  • Bigg Denni
  • Pomm'E Zhak
  • Liberator Ann-Mari
RU2275369C2
DERIVATIVES OF IMIDAZOLE MODULATING SODIUM CHANNEL 2002
  • Bigg Denni
  • Pomm'E Zhak
  • Liberator Ann-Mari
RU2296565C2
NEW HETEROCYCLIC COMPOUNDS AS PHARMACEUTICALS 2000
  • Ovehn Serzh
  • Shabrie De Lasson'Er P'Er-Eht'Enn
RU2260009C2
NOVEL DERIVATIVES OF ARYLIMIDAZOLE, THEIR PREPARATIONS AND THEIR THERAPEUTIC USES 2003
  • Bigg Denni
  • Liberator Ann-Mari
  • Shabri De Lasson'Er P'Er-Eht'Enn
RU2323216C2
DERIVATIVES OF 2-(IMINOMETHYL)AMINOPHENYL, METHODS OF SYNTHESIS, PHARMACEUTICAL COMPOSITION 1998
  • Ovehn Serzh
  • Kharnett Dzheremiakh
  • Bigg Denni
  • Shabrie De Ljazonn'Er P'Er-Eht'Enn
RU2202543C2
BETA-CARBOLINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF AND METHODS FOR BINDING, ATTAINMENT OF AGONISTIC/ANTAGONISTIC EFFECT 1999
  • Tjurio Kristof Alan
  • Puatu Lidi Fransin
  • Gal'Sera Mari-Odil'
  • Muane Kristof Filipp
  • Gordon Tomas D.
  • Morgan Barri A.
  • Bigg Dennis S. Kh.
  • Pomm'E Zhak
RU2233841C2

RU 2 271 355 C2

Authors

Shabrie De Lasson'Er P'Er-Eht'Enn

Kharnett Dzheremia

Bigg Denni

Pomm'E Zhak

Lannua Zhak

Liberator Ann-Mari

Tjur'O Kristof

Dates

2006-03-10Published

2000-10-10Filed