FIVE-MEROUS HETEROCYCLE DERIVATIVES, METHOD FOR PREPARING AND USING THEM AS THERAPEUTIC AGENTS Russian patent published in 2014 - IPC C07D277/24 C07D277/30 C07D277/28 A61K31/426 A61P25/00 

Abstract RU 2530882 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to using compounds of general formula (I) possessing the properties of monoaminoxidase (MAO) and/or lipid peroxidation inhibitors, and/or the properties of sodium channel modulators, as well as to a based therapeutic agent possessing the same properties, more specifically the compounds and therapeutic agent can be used for treating the Parkinson's disease, senile dementia, Alzheimer disease, Huntington's chorea, amyotrophic lateral sclerosis, schizophrenia, depressions, psychosis, pain and epilepsy. In general formula (I) X means S; A means radical (a), wherein Q means OH, two of the radicals R19, R20 and R21 mean alkyl, while the third one means H; B means H, n means 0 or 1, both R1 and R2 mean H, and Ω means: either the radical NR46R47, wherein one of R46 and R47 means H or hydroxyalkyl, alkynyl or cyanoalkyl, while the other one means H or alkyl; or the radical OH.

EFFECT: preparing the compounds of general formula (I) possessing the properties of the monoaminoxidase (MAO) inhibitors.

4 cl, 349 ex

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RU 2 530 882 C2

Authors

Shabrie De Lasson'Er P'Er-Eht'Enn

Kharnett Dzheremia

Bigg Denni

Pomm'E Zhak

Lannua Zhak

Liberator Ann-Mari

Tjur'O Kristof

Dates

2014-10-20Published

2009-10-02Filed