DERIVATIVES OF FIVE-MEMBER HETEROCYCLES, METHOD OF PRODUCTION AND USE THEREOF AS MEDICINAL AGENTS Russian patent published in 2010 - IPC C07D233/66 A61K31/4164 A61P25/00 

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of general formula (III): in racemic form, in enantiometic form or in form of any combination of these forms, in which Het represents a five-member heterocycle containing 2 heteroatoms, where general formula (III) corresponds to only one of the following formulae , , in which: n = 1, A is biphenyl or cyclohexylphenyl, B is a hydrogen atom, R₁ and R₂ each independently represents a hydrogen atom, X is NR³, where R³ is a hydrogen atom, and Ω is a NR⁴⁶R⁴⁷ radical, where R⁴⁶ is a -COOR⁵¹ radical, where R⁵¹ is alkyl, cycloalkyl, cycloalkylalkyl or alkoxyalkyl and R⁴⁷ is a hydrogen atom, and a salt of such a compound, as well as to a pharmaceutical composition based on the said compounds. Formula (III) compounds can be used to prepare a medicinal agent for inhibiting monoamine oxidase and/or lipid peroxidation, and/or as sodium channel modulators.

EFFECT: obtaining a medicinal agent for treating or preventing pain and neuropathic pain.

12 cl, 349 ex