FIELD: biotechnology, immunology, medicine.
SUBSTANCE: antigens for vaccine against influenza virus are prepared by preparing the crude viral concentrate and purification of viral concentrate is carried out by gel-filtration method on carrier "DIOL-500". Then viral concentrate is cleaved with detergent β-octylglucoside and vaccine antigens are isolated by gel-filtration method on carrier Sephadex G-50. Advantage of invention involves enhancing prophylactic properties of antigens of influenza viruses. Invention can be used in producing anti-influenza vaccine used in prophylaxis of influenza in population for aim reducing risk and complications of the disease.
EFFECT: improved preparing method.
6 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| INACTIVATED SPLIT INFLUENZA VACCINE AND PREPARATION METHOD THEREOF | 2015 |
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RU2584594C1 |
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| INFLUENZA VACCINE AND METHOD FOR PREPARING IT | 2010 |
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| TEST SYSTEM FOR DETERMINING SPECIFIC ACTIVITY OF INFLUENZA VIRUS AND METHOD FOR ITS OBTAINING | 2022 |
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