FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine, and concerns a method of preparing a influenza vaccine. Substance of the invention includes influenza virus infection of chicken embryos, incubation, sampling of a virus-containing fluid, purification of influenza virus, concentration and final virus purification by gel filtration HW-65C carrier column chromatography. Purified virions are destroyed by the detergent β-octylglucoside to be removed then. Three half-finished vaccines prepared with the use of received with use of H1N1, H3N2 and B serotypes are combined so that the hemagglutinin concentration in each serotype is about 30 mcg/ml.
EFFECT: reduction in price of the method of preparing the influenza vaccine and its improvement.
5 ex, 1 tbl
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