FIELD: fine organic synthesis, in particular production of triterpene compounds, betulin, useful in pharmaceutical and cosmetic industry.
SUBSTANCE: betulin is isolated from birch bark by extraction with neutral organic solvents, namely dioxan aqueous solution containing 0-20 mass % of water.
EFFECT: accelerated extraction process, increased yield of target product, decreased concentration of ester contaminants, and simplified betulin purification.
1 cl, 7 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| WAY OF RECEPTION OF BIOLOGICALLY ACTIVE SUBSTANCES FROM BIRCH BARK | 2008 |
|
RU2363486C1 |
| METHOD OF BIRCH BARK CONVERSION | 2008 |
|
RU2352349C1 |
| METHOD FOR PREPARING BETULIN AND LUPEOL | 2004 |
|
RU2270202C1 |
| METHOD OF BIRCH BARK CONVERSION | 2008 |
|
RU2352350C1 |
| METHOD FOR PREPARING BETULIN | 2004 |
|
RU2270201C1 |
| METHOD OF OBTAINING BETULIN (VERSIONS) | 2013 |
|
RU2523545C1 |
| METHOD OF PROCESSING BIRCH BARK TO OBTAIN BETULIN AND SUBERIC ACIDS | 2011 |
|
RU2460741C1 |
| METHOD FOR PREPARING BETULINIC ACID | 2004 |
|
RU2269541C1 |
| METHOD FOR PRODUCING BETULONIC ACID | 2014 |
|
RU2568881C1 |
| METHOD OF PROCESSING BIRCH BARK TO OBTAIN BETULIN AND SUBERIC ACIDS | 2016 |
|
RU2620814C1 |
