FIELD: chemistry.
SUBSTANCE: method involves extraction of betulin from birch bark using methyl tert-butyl ether. The bark is the treated with aqueous NaOH solution. The aqueous alkaline solution discharged from the birch bark for extracting suberic acids is treated with sulphuric acid solution. Purification of betulin from impurities in an organic extract is carried out via concentration followed by hot washing with NaOH solution and then with water, while simultaneously distilling residual methyl tert-butyl ether from the betulin. The method enables to obtain betulin and suberic acids without additional purification steps.
EFFECT: environmental safety and cost effectiveness.
2 ex
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Authors
Dates
2012-09-10—Published
2011-04-05—Filed