METHOD FOR EVALUATING THYROID DYSFUNCTION TREATMENT EFFECTIVENESS Russian patent published in 2006 - IPC G01N33/92 G01N33/78 

FIELD: medicine.

SUBSTANCE: method involves determining thyrotropic hormone (TTH), free thyroxin (FR T4), total cholesterol (TCHS) and β-lipoproteins (β-LP) concentration before and after treatment. Dimensionless integral biochemical index IE is calculated as where <TTH>, <FR T4>, <TCHS> and <β-LP> are the centers of normative blood concentration change intervals of thyrotropic hormone (TTH), free thyroxin (FR T4), total cholesterol (TCHS) and β-lipoproteins (β-LP) concentration, and σ_TTH, σ_{FR T4}, σ_TCHS and σ_βLP are quarters of the corresponding intervals, respectively. Index IE value being increased after the treatment, functional thyroid gland activity becomes worse and the treatment is considered to be ineffective. IE value being reduced, functional thyroid gland activity becomes better and the treatment is considered to be effective.

EFFECT: high accuracy of evaluation; enhanced effectiveness in predicting hypothyroidism and cardiovascular disorder development.