FIELD: organic chemistry.
SUBSTANCE: invention is related to a method for producing methyl 3-benzoyl-4-hydroxy-1-(2-hydroxyphenyl)-2-(1Η-indol-3-yl)-5-oxo-2,5-dihydro-1Η-pyrrole-2-carboxylate with formula ΙΙ by holding 3-benzoyl-2-hydroxy-3a-(1H-indol-3-yl)-1Η-pyrrolo[2,1-c][1,4]benzoxazine-1,4(3aΗ)-dione Ι in methanol at room temperature according to the following scheme:
EFFECT: invention enables development of a simple method for synthesis of methyl 3-benzoyl-4-hydroxy-1-(2-hydroxyphenyl)-2-(1Η-indol-3-yl)-5-oxo-2,5-dihydro-1Η -pyrrole-2-carboxylate, which has antimicrobial activity.
1 cl, 1 tbl, 2 ex
| Title |
Year |
Author |
Number |
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|
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2021 |
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