FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing a novel compound N,N-diethyl-3-benzoyl-4-hydroxy-1-(2-hydroxyphenyl)-2-(1H-indol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxamide of formula II by holding 3-benzoyl-2-hydroxy-3a-(1H-indol-3-yl)-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,4(3aH)-dione I with diethylamine at room temperature according to the following scheme:
EFFECT: novel method of producing a compound of N,N-diethyl-3-benzoyl-4-hydroxy-1-(2-hydroxyphenyl)-2-(1H-indol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxamide, having antimicrobial activity, has been developed.
1 cl, 1 tbl, 2 ex
| Title |
Year |
Author |
Number |
| METHOD FOR PRODUCING METHYL 3-BENZOYL-4-HYDROXY-1-(2-HYDROXYPHENYL)-2-(1H-INDOL-3-YL)-5-OXO-2,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLATE HAVING ANTIMICROBIAL ACTIVITY |
2023 |
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
- Kobelev Aleksandr Ivanovich
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|
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|
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|
RU2785345C1 |
| 3A-(4-R-PHENYL)-2-HYDROXY-3-(3-OXO-3,4-DIHYDROQUINOXALIN-2-YL)BENZO[D]PYRROLO[2,1-B]THIAZOL-1(3AH)-ON |
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RU2783288C1 |
