FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing a novel compound N,N-diethyl-3-benzoyl-4-hydroxy-1-(2-hydroxyphenyl)-2-(1H-indol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxamide of formula II by holding 3-benzoyl-2-hydroxy-3a-(1H-indol-3-yl)-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,4(3aH)-dione I with diethylamine at room temperature according to the following scheme:
EFFECT: novel method of producing a compound of N,N-diethyl-3-benzoyl-4-hydroxy-1-(2-hydroxyphenyl)-2-(1H-indol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxamide, having antimicrobial activity, has been developed.
1 cl, 1 tbl, 2 ex
Title |
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