FIELD: organic chemistry, chemical technology.
SUBSTANCE: invention relates to a method for preparing new individual compounds of the class indole-3-spiro-pyrrols of the formula:
wherein R means CH2C6H5 (I), C6H11-c (II); Ar means p-NO2C6H4 (I), C6H5 (II); Ar' means C6H5 (I), p-ClC6H4 (II). Method involves interaction of 1-aryl-4-aroyl-5-methoxycarbonyl-2,3-dihydro-2,3-pyrrolidone of the formula:
with 3-alkylamino-5,5-dimethylcyclohexene-2-one-1 of the formula: 
in medium with inert aprotonic solvent, for example, absolute benzene at temperature 79-80oC followed by isolation of end products. Synthesized compounds can be sued as the parent product for synthesis of new heterocyclic systems.
EFFECT: improved preparing method.
3 cl, 2 sch, 2 ex
| Title |
Year |
Author |
Number |
| ANALGESIC MEDICATION |
2007 |
- Racheva Nadezhda L'Vovna
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
- Fedorovtseva Anastasija Nikolaevna
|
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2005 |
- Maslivets Andrej Nikolaevich
- Bannikova Julija Nikolaevna
- Shkljaev Jurij Vladimirovich
- Rozhkova Julija Sergeevna
- Smirnova Aleksandra Sergeevna
- Aleksandrova Galina Arsent'Evna
|
RU2281286C1 |
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2005 |
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|
RU2294330C1 |
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2007 |
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|
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2012 |
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|
RU2520005C2 |
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2008 |
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|
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2011 |
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|
RU2467011C1 |
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2008 |
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|
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2012 |
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2006 |
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|
RU2316557C1 |
