TRANSPLANT FOR CORRECTION OF CONNECTIVE TISSUE DEFECTS AND METHOD OF PRODUCTION THEREOF Russian patent published in 2008 - IPC A61K35/32 A61K35/12 A61K35/28 C12N5/08 A61P43/00 

FIELD: medicine.

SUBSTANCE: invention refers to production of genetically unmodified fibroblast cell cultures, multipotent mesenchymal stromal cells, marrow mononuclear leukocytes, and to production of combined transplant with matrix-carrier. Invention represents combined transplant for correction of connective tissue defects, characterised by that it contains cell cultures of marrow mononuclear leukocytes or multipatent mesenchymal stromal cells or human fibroblasts and matrix-carrier, produced by mixing of specified components, thus substratum is laminated with cell suspension of allogenic or autogenic cell culture at rate 5-10 million cells per 1 cm³, substrata with attached cells are wash out in Hanks' medium.

EFFECT: invention provides evident stimulating action on connective tissue growth within engraftment area.

6 cl, 1 ex