BIOTRANSPLANT, METHOD FOR MAKING THEREOF AND METHOD OF TREATING DEGENERATIVE AND TRAUMATIC DISEASES OF MAXILLOFACIAL BONE TISSUE Russian patent published in 2010 - IPC A61K35/28 A61P19/00 

Abstract RU 2380105 C1

FIELD: medicine.

SUBSTANCE: invention concerns medicine and represents a biotransplant for treating degenerative and traumatic diseases of bone tissue, characterised by that it contains autologous or donor multipotent mesenchymal stromal cells (MMSCs) of bone marrow or fatty tissue of adult donors which are distributed in a fibrinous clot in concentration 5-7 million cells per 1 ml, representing polymerised thrombocyte-enriched blood plasma of the patient, and a carrier based on collagen-mineral complex with identical composition as natural bone material, or biocompatible polymer.

EFFECT: invention provides creation of biological transplant for replacement of bone defects which is built-in in new-grown tissues, stimulates regeneration of tissues, while being a source of bone youth that leads to organotypic regeneration of bone tissue within defect and complete degradation of material in preset terms with reduction of by-effects.

6 cl, 3 ex

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RU 2 380 105 C1

Authors

Gol'Dshtejn Dmitrij Vadimovich

Kulakov Anatolij Alekseevich

Volkov Aleksej Vadimovich

Makarov Andrej Vital'Evich

Alekseeva Irina Sergeevna

Arutjunjan Irina Vladimirovna

Dates

2010-01-27Published

2008-07-29Filed