FIELD: medicine, orthopedics, oral surgery, surgical stomatology.
SUBSTANCE: the present innovation refers to the system of delivering medicinal preparations and could be applied for filling in osseous defects or as a matrix for cell cultures. Porous hydroxyapatite ceramics with bimodal distribution of pores contains thin intragranular (under 10 mcm diameter) and large-scale interpenetrating intergranular pores, the size being above 100 mcm, at total quantity of about 41-70 rot.%. The method deals with manufacturing spherical granules of about 400-600 mcm diameter that contain hydroxyapatite powder and gelatin, pressing these spherical granules under 10-100 MPa pressure and thermal treatment at about 900-1250°C at keeping from 30 to 300 min. The innovation enables to create ceramics with bimodal distribution of pores.
EFFECT: higher efficiency of manufacturing.
2 cl, 1 tbl
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