BENZOTRIAZEPINES AS GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS Russian patent published in 2007 - IPC A61K31/55 C07D255/04 A61P1/00 

Abstract RU 2304438 C2

FIELD: organic chemistry, medicine, pharmacology, pharmacy.

SUBSTANCE: invention relates to using compound of the formula (I) for preparing a medicinal agent used in treatment of disturbances associated with gastrin, and to a method for treatment of these disorders, a pharmaceutical composition used in treatment of said disturbances and containing a proton pump inhibitor, and a compound of the formula (I). Also, invention relates to a method for preparing the pharmaceutical composition, a set containing a compound of the formula (I) and the proton pump inhibitor. Also, invention relates to novel compounds of formulas (IIa) and (IIb) . Invention provides the enhanced effectiveness of treatment.

EFFECT: improved, enhanced and valuable properties of compounds and pharmaceutical composition.

50 cl, 1 tbl, 160 ex

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RU 2 304 438 C2

Authors

Makdonal'D Jehjn Mehjr

Bak Ildiko Marija

Kharper Ehlehjn Ehnn

Linni Jan Dunkan

Peter Majkl Dzhon

Stil Kehtrin Izobel' Mehri

Ostin Kehrol

Danstoun Dehvid Dzhon

Kalindzhan Sarkis Barret

Lou Kehrolajn Minli Rehchel

Spenser Dzhon

Rajt Pol Trevor

Dates

2007-08-20Published

2002-11-12Filed