FIELD: organic chemistry, pharmaceuticals.
SUBSTANCE: disclosed are compounds of general formula I 
and pharmaceutically acceptable salts thereof, wherein R1 and R3 are hydrogen or C1-C4-alkyl; R2, R4, R5 are hydrogen; R6, R7, R8, R9 are hydrogen, C1-C4-alkyl, C1-C4-alkoxy, F, Cl, Br, I; or R8 and R9 together with phenyl ring attached thereto form naphthalene fragment; A is -SO2-. Compounds of present invention are useful as anti-arrhythmic drugs with cardioprotective components in prophylaxis and treatment of infarct. Also described is drug based on the compounds of formula I.
EFFECT: new drug for prophylaxis and treatment of infarct.
17 cl, 11 ex
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|
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|
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- Vajkhert Andreas
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- Shol'Ts Vol'Fgang
|
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