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(19)

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2 306 333

(13)

(51)

IPC

C12N1/19(2006-01-01)

C12N15/09(2006-01-01)

C07K14/765(2006-01-01)

C12R1/84(2006-01-01)

(21) (22)

Application

2005116181/13, 2005-05-27

(24)

Start date

2005-05-27

(22)

Actual filing date

2005-05-27

(45)

Published

2007-09-20

(72)

Inventor

Novikov Dmitrij ViktorovichPervushkin Petr MikhajlovichNovikov Viktor Vladimirovich

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennost'Ju Nauchno-Proizvodstvennaja Kompanija I Kletochnye Tekhnologii"

YEAST Pichia pastoris X-33/2albumin STRAIN FOR SECRETION OF HUMAN ALBUMIN Russian patent published in 2007 - IPC C12N1/19 C12N15/09 C07K14/765 C12R1/84

Abstract RU 2306333 C2

FIELD: gene engineering, in particular yeast strain modified by introducing of foreign genetic material.

SUBSTANCE: claimed strain is obtained by transforming of starting culture Pichia pastoris X-33 with two albumin structural genes with signals of yeast alpha-factor secretion, transcribed under control of 5'AOX1 promoter and transcription termination region of hepatitis G virus. Strain of present invention is useful in production of albumin-containing drugs.

EFFECT: strain for production of human recombinant albumin of increased yield.

3 ex

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RU 2 306 333 C2

Authors

Novikov Dmitrij Viktorovich

Pervushkin Petr Mikhajlovich

Novikov Viktor Vladimirovich

Dates

2007-09-20—Published

2005-05-27—Filed