FIELD: biotechnology, microbiology.
SUBSTANCE: invention relates to yeast strain Pichia pastoris PS106(pHIG) that represents a producer of human immune interferon, to recombinant plasmid used for transformation of this strain, and to a method for design of such plasmid. Invention provides preparing a recombinant gamma-interferon that can be secreted into cultural fluid in industrial scales. Advantage of invention involves the development of plasmid able to produce recombinant gamma-interferon for large-scale production.
EFFECT: valuable properties of yeast strain.
3 cl, 2 dwg, 3 ex
| Title |
Year |
Author |
Number |
| STRAIN OF YEAST PICHIA PASTORIS PS105(PBIG) AS PRODUCER OF BOVINE INTRACELLULAR IMMUNE INTERFERON, RECOMBINANT PLASMID DNA PBIG PROVIDING BIOSYNTHESIS OF BOVINE INTRACELLULAR IMMUNE INTERFERON AND METHOD FOR CONSTRUCTING RECOMBINANT PLASMID DNA PBIG |
2002 |
- Gradoboeva A.E.
- Padkina M.V.
- Parfenova L.V.
- Sambuk E.V.
- Smirnov M.N.
|
RU2231545C1 |
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2000 |
- Padkina M.V.
- Parfenova L.V.
- Sambuk E.V.
- Smirnov M.N.
|
RU2180687C1 |
| STRAIN OF YEAST PICHIA PASTORIS AS PRODUCER OF LEUKOCYTE HUMAN INTERFERON-16, RECOMBINANT PLASMID DNA PHIN AND METHOD FOR ITS CONSTRUCTION |
2002 |
- Padkina M.V.
- Parfenova L.V.
- Sambuk E.V.
- Smirnov M.N.
|
RU2203950C1 |
| PICHIA PASTORIS YEAST STRAIN - PRODUCER OF CHICKEN INTERFERON-GAMMA, RECOMBINANT PLASMID DNA WHICH FACILITATES BIOSYNTHESIS CHICKEN INTERFERON-GAMMA, AND CONSTRUCTION METHOD THEREOF |
2006 |
- Padkina Marina Vladimirovna
- Gradoboeva Anastasija Evgen'Evna
- Sambuk Elena Viktorovna
- Smirnov Mikhail Nikolaevich
|
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2006 |
- Padkina Marina Vladimirovna
- Zinov'Eva Julija Grigor'Evna
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|
RU2315105C1 |
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2020 |
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|
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2000 |
- Padkina M.V.
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|
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| RECOMBINANT PLASMIDE DNA pCPBH FOR BIOSYNTHESIS OF POLYPEPTIDE WITH HUMAN CARBOXYPEPTIDASE B PROPERTIES AND RECOMBINANT STRAIN OF METHYLOTROPHIC YEASTS PICHIA PASTORIS - PRODUCENT OF POLYPEPTIDE WITH HUMAN CARBOXYPEPTIDASE B PROPERTIES |
2011 |
|
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2017 |
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|
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|
RU2800472C2 |
