IMPROVED SEPARATION Russian patent published in 2007 - IPC A61K35/14 A61P7/00 A61L33/00 A61J1/05 G01N33/49 A61M1/00 A61P31/04 

FIELD: biochemical methods.

SUBSTANCE: invention provides a method for binding and separating at least one component from a body fluid. Body fluid, such as whole blood, is passed through integral separating matrix without displacing components according their sizes from the matrix, the latter having porous structure with pore size within a range of 5 to 500 μm and active surface between 0.5 and 10 m². During passage, at least one component of the body fluid binds to at least one functional group in the matrix. Matrix is prepared by one of following methods: caking, molding, or foaming. Use of bile acid residue immobilized of a carrier is proposed to eliminate a component from aqueous solution containing it. Invention further provides device for selective binding of at least one component from body fluid comprising case with inlet and outlet and at least one separation matrix, said matrix being rigid and integral during passage of the body fluid therethrough.

EFFECT: achieved selectivity in separation of at least one component from a body fluid.

32 cl, 4 dwg, 2 tbl, 35 ex