METHOD FOR RESTRICTING THE NECROSIS AREA WITH ROXYTROMYCIN WHILE MODELING CORONARY OCCLUSION MYOCARDIAL INFARCTION IN ANIMALS Russian patent published in 2008 - IPC A61K31/365 A61P9/10 

Abstract RU 2318506 C1

FIELD: medicine, experimental cardiology.

SUBSTANCE: the present innovation deals with restricting the necrosis area in the course of experimental coronary occlusion myocardial infarction due to intragastric introduction of roxytromycin at the dosage of 30 mg/kg 15 min before coronary occlusion. The innovation provides significant decrease of the necrosis area due to cardioprotector action of roxytromycin.

EFFECT: higher efficiency.

1 ex, 1 tbl

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RU 2 318 506 C1

Authors

Chernomortseva Elena Stanislavovna

Pokrovskij Mikhail Vladimirovich

Pokrovskaja Tat'Jana Grigor'Evna

Kharchenko Vladimir Vasil'Evich

Kochkarov Vladimir Iskhakovich

Stepina Irina Viktorovna

Artjushkova Elena Borisovna

Gasanov Melik Tofikovich

Muljar Aleksandr Georgievich

Rjazaeva Lidija Maksimovna

Mantulina Lilija Alekseevna

Gladchenko Mikhail Petrovich

Kljavs Jurij Petrovich

Gureev Vladimir Vladimirovich

Muminova Kamila Kamil'Dzhanovna

Dates

2008-03-10Published

2006-07-14Filed