METHOD FOR RESTRICTING THE NECROSIS AREA WITH CLARITROMYCIN WHILE MODELING CORONARY OCCLUSION MYOCARDIAL INFARCTION IN ANIMALS Russian patent published in 2008 - IPC A61K31/365 A61P9/10 

Abstract RU 2318507 C1

FIELD: medicine, experimental cardiology.

SUBSTANCE: one should intragastrically introduce claritromycin at the dosage of 30 mg/kg 15 min before coronary occlusion in the course of experimental coronary occlusion myocardial infarction. The innovation provides significant decrease of the necrosis area due to cardioprotector action of claritromycin.

EFFECT: higher efficiency.

1 ex, 1 tbl

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RU 2 318 507 C1

Authors

Chernomortseva Elena Stanislavovna

Pokrovskij Mikhail Vladimirovich

Pokrovskaja Tat'Jana Grigor'Evna

Kharchenko Vladimir Vasil'Evich

Kochkarov Vladimir Iskhakovich

Stepina Irina Viktorovna

Artjushkova Elena Borisovna

Gasanov Melik Tofikovich

Muljar Aleksandr Georgievich

Smirnova Evdokija Ivanovna

Rjazaeva Lidija Maksimovna

Mantulina Lilija Alekseevna

Gladchenko Mikhail Petrovich

Kljavs Jurij Petrovich

Gureev Vladimir Vladimirovich

Dates

2008-03-10Published

2006-07-14Filed