FIELD: medicine.
SUBSTANCE: method involves incubating blood serum and DNA with following recording DNA and antibodies interaction. Electrochemical cell parameter measurement plots are interpreted as diagnostic signs of antibody presence in blood serum. An electrochemical cell has measurement electrode and comparison electrode. Blood serum and DNA incubation takes place on measurement electrode which surface is covered in advance with polyaniline. Silver chloride electrode is used as comparison electrode. Blood serum samples are diluted with buffer solution in 1:(20-50) proportion.
EFFECT: high accuracy in determining antibodies in blood serum.
6 dwg, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| ELECTROCHEMICAL METHOD FOR DETERMINING SPECIFIC ANTIBODIES IN BLOOD SERUM BY MEANS OF PROTEINS LABELED WITH METALS | 2002 |
|
RU2249217C2 |
| DEVICE FOR DETERMINATION OF BIOLOGICALLY ACTIVE COMPOUNDS IN BIOLOGICAL FLUIDS AND PROCESS OF MANUFACTURE OF SENSITIVE ELEMENT | 1991 |
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| METHOD OF ELECTROCHEMICAL INDICATION OF IMMUNO-CHEMICALLY ACTIVE MACROMOLECULES IN EXAMINED SOLUTIONS | 1997 |
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| BIOSENSOR FOR SIMULTANEOUS GLUCOSE AND BLOOD LACTATE DETERMINATION | 2018 |
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| VOLTAMPEROMETRIC METHOD FOR ALDOSTERONE QUANTITATIVE ASSAY | 2007 |
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| METHOD OF BLOOD PLASMA PROXIMATE ANALYSIS FOR CARDIOMYOGLOBIN BY MEANS OF ELECTROCHEMICAL IMMUNOSENSOR | 2009 |
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| METHOD OF DETERMINATION OF ANTIBODIES IN BLOOD SERUM | 0 |
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SU1832198A1 |
| METHOD OF QUANTITATIVE ELECTROCHEMICAL ANALYSIS OF BIOLOGICAL MOLECULES | 1998 |
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RU2161653C2 |
