BENZAMIDE 4-(PHENYL-PIPERAZIN-METHYL) DERIVATIVES AND THEIR APPLICATION FOR TREATMENT OF PAIN AND GASTROENTERIC UPSET Russian patent published in 2008 - IPC C07D295/155 C07D405/06 A61K31/496 A61P25/04 

Abstract RU 2326875 C2

FIELD: chemistry.

SUBSTANCE: invention refers to benzamide 4-(phenyl-piperazin-methyl) derivatives of the general formula I in which R1 - aryl, heteroaryl, selected from the group which includes difuryl, pyridyl and thienyl; R2 - hydrogen or C1-12 alkyl. The methods of preparation of the compounds, pharmaceutical composition on their basis and application while preparing medicines are described.

EFFECT: compounds can be applied to treatment of pain and functional gastroenteric upset.

8 cl, 1 ex

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RU 2 326 875 C2

Authors

Braun Uil'Jam

Griffin Ehndrju

Plobek Niklas

Uolpol Kristofer

Dates

2008-06-20Published

2003-11-05Filed