Show metadata Hide metadata

(19)

(11)

2 333 223

(13)

(51)

IPC

C08B37/00(2006-01-01)

C07K17/12(2006-01-01)

A61K39/385(2006-01-01)

A61K47/48(2006-01-01)

(21) (22)

Application

2006107546/04, 2004-08-12

(24)

Start date

2004-08-12

(22)

Actual filing date

2004-08-12

(45)

Published

2008-09-10

(72)

Inventor

Dzhain SandzhajLejng PiterGregoriadis GregoriKhrechuk-Kherst Dejl GovardPapaioannu Ioannis

(73)

Holder

Lajpoksen Teknolodzhiz Limited

ALDEHYDE DERIVATIVES OF SIALIC ACID, METHODS OF THEIR OBTAINMENT, CONJUGATES OF ALDEHYDE DERIVATIVES OF SIALIC ACID, AND PHARMACEUTICAL COMPOSITION BASED ON THEM Russian patent published in 2008 - IPC C08B37/00 C07K17/12 A61K39/385 A61K47/48

Abstract RU 2333223 C2

FIELD: chemistry.

SUBSTANCE: invention concerns aldehyde derivatives and conjugates of di-, oligo- or polysaccharide, of the general formula (I), methods of obtaining them, and pharmaceutical composition based on them and capable of staying in blood flow for prolonged time. , where R is -CH(CHO)CH₂OH, -CH₂CHO, -CH(CH₂NHR¹)CH₂OH, -CH(CH₂NHNHR¹)CH₂OH, -CH(CH=NNHR¹)CH₂OH, -CH₂CH₂NHR¹, -CH₂CH=N-NHR¹, -CH₂CH₂NHNHR¹; R¹ is polypeptide or albumen; GlyO is a sialic acid bond; R³ is H; R⁴ is OH; n is 2 or more.

EFFECT: obtaining pharmaceutical composition based on aldehyde derivatives of sialic acid capable of staying in blood flow for prolonged time.

20 cl, 7 tbl, 22 dwg, 10 ex

Similar patents RU2333223C2

Title	Year	Author	Number
POLYSIALIC ACID DERIVATIVES	2004	Khrechuk-Kherst Dejl Govard Dzhain Sandzhaj Lejng Piter Gregoriadis Gregori Papaioannu Ioannis	RU2327703C2
GLYCOPOLYSIALYLATION OF PROTEINS THAT ARE NOT THE PROTEINS OF THE BLOOD CLOTTING	2014	Dzhain Sandzhaj Gregoriadis Gregori Dvivedi Archana Nat Sridzhit Zikmann Yurgen Khajder Shtefan Rottenshtajner Khanspeter Turetsek Peter	RU2662807C2
GLYCOPOLYSIALYLATION OF PROTEINS, WHICH ARE NOT BLOOD CLOTTING PROTEINS	2010	Dzhain Sandzhaj Gregoriadis Gregori Dvivedi Archana Nat Sridzhit Zikmann Jurgen Khajder Shtefan Rottenshtajner Khanspeter Turetsek Peter	RU2533619C2
N-TAILED POLYSIALYLATION	2007	Dzhajn Sanzhaj Chzhan Zhunshen	RU2432175C2
METHOD OF REDUCING CONTENT OF ENDOTOXIN IN SAMPLE CONTAINING POLYSIALIC ACID AND ENDOTOXIN	2008	Dzhajn Sanzhaj Lajng Piter Gregoriadis Gregori	RU2473567C2
CONJUGATES OF BLOOD COAGULATION PROTEINS	2010	Zikmann Yurgen Khajder Shtefan Rottenshtajner Khanspeter Turetsek Peter	RU2595442C2
BLOOD COAGULATION PROTEIN CONJUGATES	2010	Zikmann Yurgen Khajder Shtefan Rottenshtajner Khanspeter Turetsek Peter	RU2744370C2
DRUG PREPARATION AND METHOD FOR IMPROVING RHEOLOGICAL PROPERTIES OF SPUTUM AND PULMONARY ADMINISTRATION OF THIS PREPARATION	2009	Muzyka Inessa Stepanovna Avtushenko Sergej Sergeevich Surkov Kirill Gennadievich Romanov Vadim Dmitrievich Genkin Dmitrij Dmitrievich	RU2522846C2
HUMAN OXYNTOMODULIN, ITS APPLICATION, MEDICATION BASED THEREON AND METHOD OF APPLYING MEDICATION FOR TREATMENT AND PREVENTION OF HYPERGLYCEMIA	2009	Esipov Roman Stanislavovich Stepanenko Vasilij Nikolaevich Bejrakhova Ksenija Andreevna Miroshnikov Anatolij Ivanovich Avtushenko Sergej Sergeevich Surkov Kirill Gennadievich Romanov Vadim Dmitrievich Genkin Dmitrij Dmitrievich	RU2524204C2
METHOD FOR OBTAINING A HYBRID PROTEIN CONTAINING A FUSED PROTEIN ANALOGUE OF AN INTERFERON GAMMA CONJUGATED WITH OLIGOSACCHARIDE	2016	Martynov Aleksandr Igorevich Sankov Mikhail Nikolaevich Gasanov Vagif Ali Ogly Shevale Aleksandr Fedorovich Vlasov Aleksandr Alekseevich Shilovskij Igor Petrovich	RU2656140C2

RU 2 333 223 C2

Authors

Dzhain Sandzhaj

Lejng Piter

Gregoriadis Gregori

Khrechuk-Kherst Dejl Govard

Papaioannu Ioannis

Dates

2008-09-10—Published

2004-08-12—Filed