FIELD: medicine.
SUBSTANCE: in formula 
(1), R1 is di-C1-6alkoxyphenyl group; A is one of the following groups (i)-(vi); (i) -CO-B-, where B is C1-6alkylene group; (ii) -CO-Ba-, where Ba is C2-6alkenylene group; (iii) -CH(OH)-B-; (iv) -COCH((C)OOR3)-Bb-, where R3 is C1-6alkyl group and Bb is C1-6alkylene group. Values of the other radicals are specified in the patent claim. Invention also concerns the pharmaceutical composition exhibiting properties of a phosphodiesterase PDE4 inhibitor containing the compound under the invention; the phosphodiesterase 4 inhibitor containing as an active component the compound of the invention; preventive or therapeutic preparation for atopic dermatitis containing as an active component the compound of the invention.
EFFECT: higher effectiveness of application of the compound.
8 cl, 24 tbl, 262 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOL DERIVATIVES FOR TREATMENT OF TUBERCULOSIS | 2004 |
|
RU2365593C2 |
| OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | 2006 |
|
RU2418793C2 |
| NOVEL WATER-SOLUBLE PRODRUGS | 2005 |
|
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| N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS EFFECTIVE AS MONOAMINE REUPTAKE INHIBITORS | 2006 |
|
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| CARBOSTYRIL COMPOUND | 2005 |
|
RU2430920C2 |
| 1-SUBSTITUTED 4-NITROIMIDAZOLE DERIVATIVE AND METHOD OF ITS PRODUCTION | 2003 |
|
RU2324682C2 |
| PIPERAZINE DERIVATIVES | 1994 |
|
RU2124511C1 |
| AGENT FOR INHIBITING CYTOKININ SIGNAL FUNCTION | 2007 |
|
RU2477046C2 |
| NOVEL PHENYL PYRROLE DERIVATIVE | 2009 |
|
RU2470917C2 |
| PYRIDYL DIMETHYLSULPHONIC DERIVATIVE | 2006 |
|
RU2404968C2 |
