FIELD: chemistry, biochemistry.
SUBSTANCE: invention relates to biotechnology and to methods of producing vaccine preparations with the help of gene engineering and immunology. The invention proposes the expressive plasmid DNA p-BMC-gag (A)-hum, containing an artificial gene gag (A)-hum, for expression of p55 protein in eukaryote cell. The invention can be used in medicine and allied industries ensure a 10-12-fold increase in expression of p55 protein of the human immunodeficiency virus of the 1st type in eukaryote cells.
EFFECT: high-efficiency method of producing vaccine preparations gene engineering and immunology.
1 cl, 2 dwg, 2 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| pBMC-gp140(A)-hum EXPRESSION PLASMA DNA | 2006 |
|
RU2346044C2 |
| RECOMBINANT PLASMID DNA pBMC-RT(A)-hum FOR EXPRESSING PROTEIN OF REVERSE TRANSCRIPTASE OF HUMAN IMMUNODEFICIENCY VIRUS | 2006 |
|
RU2355764C2 |
| EXPRESSION PLASMID DNA pBMC - nef (A)-hum | 2006 |
|
RU2335540C1 |
| RECOMBINANT PLASMID DNA PBMC-GAG(A)MOD FOR EXPRESSION OF HUMAN IMMUNODEFICIENCY VIRUS PROTEIN GAG IN EUCARYOTIC CELLS | 2003 |
|
RU2241752C1 |
| RECOMBINANT PLASMID DNA PBMC-RT(A)M-1 USED FOR EXPRESSION OF HUMAN IMMUNODEFICIENCY VIRUS REVERSE TRANSCRIPTASE (RT)IN HIGHER EUCARYOTIC CELLS | 2003 |
|
RU2238977C1 |
| RECOMBINANT PLASMID DNA PBMC-QP120(A)M-1 FOR IMMUNIZATION AGAINST HUMAN IMMUNODEFICIENCY VIRUS | 2003 |
|
RU2227161C1 |
| RECOMBINANT PLASMID DNA pBMC-nef(A)m-1 EXPRESSING PROTEIN NEF OF HUMAN IMMUNODEFICIENCY VIRUS TYPE I VIRUS IN EUCARYOTIC CELLS | 2003 |
|
RU2229518C1 |
| NUCLEIC ACID SEQUENCE ENCODING HIV-1 GAG PROTEIN, METHOD FOR ITS PREPARING, VECTOR CONTAINING THEREOF, PROTEIN ENCODED BY ITS, PHARMACEUTICAL COMPOSITION AND THEIR USING IN PROPHYLAXIS AND/OR TREATMENT OF HIV-INFECTION AND AIDS | 2002 |
|
RU2312896C2 |
| SYSTEMS FOR EXPRESSION OF NEWCASTLE DISEASE VIRUS RECOMBINANT RNA AND VACCINES | 1999 |
|
RU2270864C2 |
| CODON-OPTIMISED HAIPL1-ENCODING NUCLEOTIDE SEQUENCE AND EXPRESSION VECTOR CONTAINING SAID SEQUENCE | 2021 |
|
RU2785621C1 |
