METHOD OF OBTAINING N,N-DIALKYL-SUBSTITUTED AMIDES OF ADAMANTYLALKYLCARBOXYLIC ACIDS Russian patent published in 2009 - IPC C07C231/12 C07C233/08 C07D211/16 

Abstract RU 2348611 C1

FIELD: chemistry.

SUBSTANCE: invention concerns chemistry of adamantane derivatives, particularly new method of obtaining N,N-dialkyl-substituted amides of adamantylalkylcarboxylic acids of the general formula

which can be of interest as semiproducts in synthesis of some bioactive substances with antivirus effect. Method involves interaction of adamantane derivative with carboxylic acid dialkylamide, where 1,3-dehydroadamantane is used as adamantane derivative, and N,N-dimethylacetamide, N,N-diethylacetamide, N-acethylpiperidine, N-propionylpiperidine, N-(2-methyl)propionylpiperidine are used as carboxylic acid dialkylamides, and process runs at reagent mol ratio of 1:2-3 respectively, in original carboxylic acid dialkylamide medium at 120-130°C for 5-6 hours.

EFFECT: alternative method of obtaining compounds of the claimed structural formula, with omitted stage of obtaining adamantylalkylcarboxylic acids.

5 ex

Similar patents RU2348611C1

Title Year Author Number
METHOD OF OBTAINING DIALKYLAMIDES OF 3-BROME-1-ADAMANTILALKANCARBON ACIDS 2007
  • Butov Gennadij Mikhajlovich
  • Mokhov Vladimir Mikhajlovich
  • D'Jakonov Sergej Vladimirovich
RU2344122C1
METHOD FOR PREPARING 3-HALOGEN-1-(ETHOXYCARBONYL)-ALKYLADAMANTANES 2006
  • Butov Gennadij Mikhajlovich
  • Mokhov Vladimir Mikhajlovich
  • D'Jakonov Sergej Vladimirovich
RU2301796C1
METHOD FOR PREPARING N-PHTHALIMIDOALKYLADAMANTANE OR ITS DERIVATIVES 2003
  • Butov G.M.
  • Mokhov V.M.
  • Vishnevskij E.N.
RU2247114C1
METHOD FOR PREPARING ADAMANTYL-CONTAINING NITRILES 2003
  • Butov G.M.
  • Mokhov V.M.
  • Vishnevetskij E.N.
RU2240310C1
METHOD OF PREPARING 1-(4-R-ARYL)ADAMANTANES AND DERIVATIVES THEREOF 2006
  • Butov Gennadij Mikhajlovich
  • Mokhov Vladimir Mikhajlovich
RU2307116C1
METHOD OF SYNTHESIS OF α-ADAMANTYL-CONTAINING ALIPHATIC AND SATURATED AROMATIC KETONES 2000
  • No B.I.
  • Butov G.M.
  • Mokhov V.M.
  • Parshin G.Ju.
RU2186760C2
METHOD FOR PREPARING 3-BROMOADMANTYL-1-ALKYL(ARYL)-KETONES 2006
  • Butov Gennadij Mikhajlovich
  • Mokhov Vladimir Mikhajlovich
  • Kunaev Roman Uazerovich
RU2309937C1
METHOD OF SYNTHESIS OF ADAMANTYL-CONTAINING β-DIKETONES AND KETOESTERS 2000
  • No B.I.
  • Butov G.M.
  • Mokhov V.M.
  • Parshin G.Ju.
  • Shevelev S.A.
  • Dalinger I.L.
RU2187493C1
METHOD FOR OBTAINING 1,3-DI(4-R-PHENYLSELENO)ADAMANTANES 2007
  • Butov Gennadij Mikhajlovich
  • Mokhov Vladimir Mikhajlovich
  • Zefirov Nikolaj Serafimovich
  • Zyk Nikolaj Vasil'Evich
  • Gavrilova Anna Jur'Evna
  • Antipin Roman L'Vovich
RU2333214C1
METHOD FOR PREPARING ALPHA-ADAMANTYL-CONTAINING ALDEHYDES 2003
  • Butov G.M.
  • No B.I.
  • Mokhov V.M.
  • Parshin G.Ju.
RU2240303C1

RU 2 348 611 C1

Authors

Butov Gennadij Mikhajlovich

Mokhov Vladimir Mikhajlovich

Dates

2009-03-10Published

2007-05-02Filed