METHOD FOR PREPARING 3-BROMOADMANTYL-1-ALKYL(ARYL)-KETONES Russian patent published in 2007 - IPC C07C49/105 C07C49/225 C07C49/403 

Abstract RU 2309937 C1

FIELD: organic chemistry, chemical technology.

SUBSTANCE: invention relates to a method for synthesis of 3-bromoadamantyl-1-alkyl(aryl)-ketones of the general formula: , wherein that can be used as intermediate substances for synthesis of some biologically active compounds. Method involves interaction of 1,3-dehydroadamantane with α-bromoketones of the following order: α-bromoacetone, α-bromoacetophenone, α-bromocyclohexanone in the mole ratio of reagents = 1:(2-3), respectively, in absolute diethyl ether medium, at temperature 34-40°C for 3-4 h. Method provides preparing the claimed compounds with high yield.

EFFECT: improved method of synthesis.

3 ex

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RU 2 309 937 C1

Authors

Butov Gennadij Mikhajlovich

Mokhov Vladimir Mikhajlovich

Kunaev Roman Uazerovich

Dates

2007-11-10Published

2006-07-11Filed