METHOD FOR PREPARATION OF CURED HYALURONIC ACID SALTS Russian patent published in 2009 - IPC C08B37/00 

Abstract RU 2366665 C1

FIELD: chemistry.

SUBSTANCE: powdered salt of hyaluronic acid is beforehand homogenised in a mixer at temperature range from 20 to 50°C in presence of at least one curing agent. The obtained homogeneous powdered mixture undergoes the simultaneous action of shear deformation and pressure in mechanochemical reactor at temperature from 20 to 50°C with pressure being in a range from 5 to 1000 MPa. The claimed method does not demand high energy and water consumption and large labour contribution and allows to use as starting materials most diverse salts of hyaluronic acid (including insoluble in water).

EFFECT: method allows to obtain the wide range of cured hyaluronic acid salts in one stage and in the absence of liquid medium.

11 cl, 15 ex

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Authors

Volkov Vladimir Petrovich

Zelenetskij Aleksandr Nikolaevich

Akopova Tat'Jana Anatol'Evna

Zhorin Vladimir Aleksandrovich

Khabarov Vladimir Nikolaevich

Seljanin Mikhail Anatol'Evich

Seljanina Ol'Ga Nikolaevna

Dates

2009-09-10Published

2007-12-03Filed