FIELD: chemistry.
SUBSTANCE: powdered salt of hyaluronic acid is beforehand homogenised in a mixer at temperature range from 20 to 50°C in presence of at least one curing agent. The obtained homogeneous powdered mixture undergoes the simultaneous action of shear deformation and pressure in mechanochemical reactor at temperature from 20 to 50°C with pressure being in a range from 5 to 1000 MPa. The claimed method does not demand high energy and water consumption and large labour contribution and allows to use as starting materials most diverse salts of hyaluronic acid (including insoluble in water).
EFFECT: method allows to obtain the wide range of cured hyaluronic acid salts in one stage and in the absence of liquid medium.
11 cl, 15 ex
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Authors
Dates
2009-09-10—Published
2007-12-03—Filed