SOLID-PHASE METHOD OF PRODUCING WATER-SOLUBLE BIOACTIVE NANOCOMPOSITE BASED ON MELANIN-MODIFIED HYALURONIC ACID SALT AND GOLD NANOPARTICLES Russian patent published in 2014 - IPC C08B37/08 B82B3/00 

Abstract RU 2532032 C1

FIELD: chemistry.

SUBSTANCE: invention relates to natural polysaccharide polymers and can be used in medicine. The obtained water-soluble bioactive nanocomposite includes a melanin compound-modified hyaluronic acid salt as a matrix and gold nanoparticles as filler. The method includes chemical reaction of solid-phase hyaluronic acid powder, a melanin compound, aurichlorohydric acid or a gold salt in conditions of simultaneous pressure action in the range of 50 to 1000 MPa and shearing deformation in a mechanochemical reactor at temperature of -18° to 110°C.

EFFECT: invention enables to obtain a water-soluble bioactive nanocomposite with high output of the end product and high content of gold.

4 cl, 18 ex

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RU 2 532 032 C1

Authors

Uspenskij Sergej Alekseevich

Khabarov Vladimir Nikolaevich

Seljanin Mikhail Anatol'Evich

Dates

2014-10-27Published

2013-03-21Filed