FIELD: chemistry.
SUBSTANCE: invention relates to natural polysaccharide polymers and can be used in medicine. The obtained water-soluble bioactive nanocomposite includes a melanin compound-modified hyaluronic acid salt as a matrix and gold nanoparticles as filler. The method includes chemical reaction of solid-phase hyaluronic acid powder, a melanin compound, aurichlorohydric acid or a gold salt in conditions of simultaneous pressure action in the range of 50 to 1000 MPa and shearing deformation in a mechanochemical reactor at temperature of -18° to 110°C.
EFFECT: invention enables to obtain a water-soluble bioactive nanocomposite with high output of the end product and high content of gold.
4 cl, 18 ex
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Authors
Dates
2014-10-27—Published
2013-03-21—Filed