CORRECTION METHOD OF FUNCTIONAL ORGANISM'S DEFECTS CAUSED BY DAMAGED NERVE CELLS OF BRAIN Russian patent published in 2009 - IPC A61K31/19 A61K31/203 A61K35/12 A61P25/00 

Abstract RU 2368378 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine and namely to neurology and can be used for correction of damaged nerve cells of the brain, which was caused by means of mitochondrial toxin of 3-nitropropionic acid. Method is implemented in the following way: stereotactic transplantation of multipotent mesenchymal stromal cells (MMSC) of human adipose tissue which is pre-incubated in the medium containing 10 mcM of retinoic acid is performed during 6 days.

EFFECT: invention allows normalising pathologic changes of brain tissue and the associated neurological deficiency owing to transplantation of pre-incubated MMSC.

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RU 2 368 378 C1

Authors

Boldyrev Aleksandr Aleksandrovich

Stepanova Marija Sergeevna

Stvolinskij Sergej L'Vovich

Rzhaninova Alla Anatol'Evna

Gol'Dshtejn Dmitrij Vadimovich

Kulikov Andrej Valentinovich

Dates

2009-09-27Published

2007-12-26Filed