FIELD: medicine.
SUBSTANCE: invention can be applied in assessment of human disadaptive processes at various pathological states. Method involves determination of met-hemoglobin, membrane-linked hemoglobin and oxidised nucleotide content and total optic erythrocyte density before and after functional sampling in the form of short-term local ischemia. Coefficient of erythrocyte resistance to ischemia K is defined on the basis of obtained data. If K is below 0 then erythrocyte resistance to ischemia is high, K values within 0 to 0.1 indicate standard resistance, and K over 0.1 indicates low resistance. Invention allows for assessment of erythrocyte resistance to functional stress, such as tissue hypoxia.
EFFECT: fast, reliable and objective detection of different types of cell adaptation to ischemia.
3 ex, 1 tbl
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Authors
Dates
2009-10-27—Published
2008-03-03—Filed