FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry, specifically to new compounds (1Z,3Z)-4-aryl-4-hydroxy-1-(3,3-dialkyl-3,4-dihydroisoquinolin-1(2N)-ylidene)-but-3-en-4-ones with general formula:
III: R=H, Alk1=Alk2=Me, Ar=Ph (a), Ar=C6H4Me-p (b), Alk1=Me, Alk2=Bu, Ar=Ph (c), Ar=C6H4Me-p (d), R=OMe, Alk1=Alk2=Me, Ar=Ph (e), Ar=C6H4Me-p (f), R=OEt, Alk1=Alk2=Me, Ar=Ph (g). The invention also relates to a method of producing said compounds.
EFFECT: obtaining new compounds with analgetic activity and which can be used as primary products in synthesis of new heterocyclic systems.
4 cl, 1 tbl, 8 ex
| Title |
Year |
Author |
Number |
| (1Z, 3Z)-4-ARYL-4-HYDROXY-1-(3,3-DIALKYL-3,4-DIHYDROISOQUINOLIN-1(2H)-YLIDENE)BUT-3-EN-4-ONES AND SYNTHESIS METHOD THEREOF |
2009 |
- Konovalova Valerija Vladislavovna
- Maslivets Andrej Nikolaevich
- Shkljaev Jurij Vladimirovich
|
RU2417221C1 |
| (2Z,5Z-1-ARYL-3-HYDROXY-5-(3,3-DIMETHYL-3,4-DIHYDROISOQUINOLIN-1(2N)-YLIDENE)-PENT-2-ENE-1,4-DIONES AND METHOD OF PRODUCING SAID COMPOUNDS |
2008 |
- Khalturina Valerija Vladislavovna
- Maslivets Andrej Nikolaevich
- Shkljaev Jurij Vladimirovich
|
RU2374232C1 |
| (1Z,3Z)-4-HYDROXY-1-(3-BUTYL-3-METHYL-3,4-DIHYDROISOQUINOLIN-1(2H)-YLIDENE)-4-(4-TOLYL)BUT-3-EN-2-ONE EXHIBITING ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY |
2009 |
- Khalturina Valerija Vladislavovna
- Maslivets Andrej Nikolaevich
- Shkljaev Jurij Vladimirovich
- Makhmudov Ramiz Ragibovich
|
RU2402534C1 |
| DIMETHYL 2-ACYL-1-HYDROXY-3-METHYL-7-OXO-6-PHENYL-2,6-DIAZABICYCLO[3,2,1]OCT-3-ENE-5,8-DICARBOXYLATES AND METHOD FOR PREPARING THEM |
2011 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2478638C1 |
| 1,6'-DIARYL-3-AROYL-4-HYDROXY-1',3'-DIMETHYLSPIRO[PIRROLE-2,5'-PYRROLO[2,3-d]PYRIMIDINE]-2',4',5(1H,1'H,3'H)-TRIONES AND METHOD FOR PRODUCTION THEREOF |
2012 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2502738C2 |
| 2-(6-ARYL-4-AROYL-3-METHYL-1-PHENYL-1H-PYRAZOLO[3,4-b]PYRIDIN-5-YL)-2-OXO-N-ARYLACETAMIDES AND METHODS FOR PRODUCTION THEREOF |
2012 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2501800C2 |
| 1,1'-DIARYL-3'-AROYL-4'-HYDROXY-1H-SPIRO [INDENO[1,2-b]PYRROL-3,2'-PYRROL]-2,4,5'-(1'H)-TRIONES AND METHOD OF THEIR OBTAINING |
2011 |
- Bubnov Nikolaj Vladimirovich
- Denislamova Ekaterina Sergeevna
- Makhmudov Ramiz Ragibovich
- Maslivets Andrej Nikolaevich
|
RU2467011C1 |
| 1'-ARYL-1-BENZYL-4'-HYDROXY-6,6-DIMETHYL-3'-CINNAMOYL-6,7-DIHYDROSPIRO[INDOLE-3,2'-PYRROLE]-2,4,5'(1H,1'H,5H)-TRIONES AND 1,1'-DIARYL-4'-HYDROXY-6,6-DIMETHYL-3'-CINNAMOYL-6,7-DIHYDROSPIRO[INDOLE-3,2'-PYRROLE]-2,4,5'(1H,1',5H)-TRIONES, EXHIBITING ANALGESIC ACTIVITY, AND METHOD FOR PRODUCTION THEREOF |
2012 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Filimonov Valerij Olegovich
- Makhmudov Ramiz Ragibovich
|
RU2520005C2 |
| METHYL 3-METHYL-5-[2-(4-ARYLAMINO)-2-OXOACETYL]-1,6-DIPHENYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLATES AND METHYL 3-METHYL-5-[2-(4-ARYLAMINO)-2-OXOACETYL]-6-STYRYL-1-PHENYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLATES AND METHOD FOR PREPARING THEM |
2012 |
- Maslivets Andrej Nikolaevich
- Bubnov Nikolaj Vladimirovich
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
- Makhmudov Ramiz Ragibovich
|
RU2495039C1 |
| (3Z)-4-ARYL-HYDROXY-1-(1,3,3-TRIMETHYLINDOLIN-2-YLIDENE)BUT-3-EN-2-ONES AND SYNTHESIS METHOD THEREOF |
2009 |
- Konovalova Valerija Vladislavovna
- Maslivets Andrej Nikolaevich
|
RU2417219C1 |
