FIELD: chemistry.
SUBSTANCE: present invention relates to organic chemistry, specifically to novel derivatives of 3,4-dihydroisoquinoline of general formula III 
where: R=H, Alk1=Alk2=Me, Ar=Ph (a), Ar=C6H4Me-n (b), Alk1Me, Alk2=Bu, Ar=Ph (c), Ar=C6H4Me-n (d), R=OMe, Alk1=Alk2=Me, Ar=Ph (e), Ar=C6H4Me-n (f), R=OEt, Alk1=Alk2=Me, Ar=Ph (g) The invention also relates to a method of producing compounds of general formula III, involving reaction of 6-aryl-2,2-dimethyl-4H-1,3-dioxin-4-ones with 3,3-dialkyl-3,4-dihydroisoquinolines in an absolute toluene medium at temperature 108-110°C, followed by extraction of the desired product.
EFFECT: obtaining novel derivatives of 3,4-dihydroisoquinoline of general formula III, having fluorescent properties, which are resistant to UV light.
4 cl, 8 ex
| Title |
Year |
Author |
Number |
| (1Z,3Z)-4-ARYL-4-HYDROXY-1-(3,3-DIALKYL-3,4-DIHYDROISOQUINOLIN-1(2N)-YLIDENE)-BUT-3-EN-4-ONES AND METHOD OF PRODUCING SAID COMPOUNDS |
2008 |
- Khalturina Valerija Vladislavovna
- Shkljaev Jurij Vladimirovich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragipovich
|
RU2374231C1 |
| (2Z,5Z-1-ARYL-3-HYDROXY-5-(3,3-DIMETHYL-3,4-DIHYDROISOQUINOLIN-1(2N)-YLIDENE)-PENT-2-ENE-1,4-DIONES AND METHOD OF PRODUCING SAID COMPOUNDS |
2008 |
- Khalturina Valerija Vladislavovna
- Maslivets Andrej Nikolaevich
- Shkljaev Jurij Vladimirovich
|
RU2374232C1 |
| (1Z,3Z)-4-HYDROXY-1-(3-BUTYL-3-METHYL-3,4-DIHYDROISOQUINOLIN-1(2H)-YLIDENE)-4-(4-TOLYL)BUT-3-EN-2-ONE EXHIBITING ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY |
2009 |
- Khalturina Valerija Vladislavovna
- Maslivets Andrej Nikolaevich
- Shkljaev Jurij Vladimirovich
- Makhmudov Ramiz Ragibovich
|
RU2402534C1 |
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2012 |
- Maslivets Andrej Nikolaevich
- Bubnov Nikolaj Vladimirovich
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
- Makhmudov Ramiz Ragibovich
|
RU2495039C1 |
| 1,6'-DIARYL-3-AROYL-4-HYDROXY-1',3'-DIMETHYLSPIRO[PIRROLE-2,5'-PYRROLO[2,3-d]PYRIMIDINE]-2',4',5(1H,1'H,3'H)-TRIONES AND METHOD FOR PRODUCTION THEREOF |
2012 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2502738C2 |
| METHYL 1-ARYL-3-HYDROXY-3'-METHYL-2,4,5'-TRIOXO-6-PHENYL-2,4,5,6-TETRAHYDRO-5'H-SPIRO[INDOLE-7,4'-ISOXAZOLE]-7a(1H)-CARBOXYLATES, METHYL 1-ARYL-(1'-PHENYL AND 1'-BENZYL)-3-HYDROXY-3'-METHYL-2,4,5'-TRIOXO-6-PHENYL-1',2,4,5,5',6-HEXAHYDROSPIRO[INDOLE-7,4'-PYRAZOLE]-7a(1H)-CARBOXYLATES AND METHYL 1'-ARYL-3'-HYDROXY-1,2',3,4'-TETRAOXO-6'-PHENYL-1,2',3,4',5',6'-HEXAHYDROSPIRO[INDENE-2,7'-INDOLE]-7a'(1'H)-CARBOXYLATES, DEMONSTRATING ANALGESIC ACTIVITY AND METHOD FOR OBTAINING THEREOF |
2014 |
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2577528C2 |
| DIMETHYL 2-ACYL-1-HYDROXY-3-METHYL-7-OXO-6-PHENYL-2,6-DIAZABICYCLO[3,2,1]OCT-3-ENE-5,8-DICARBOXYLATES AND METHOD FOR PREPARING THEM |
2011 |
- Silajchev Pavel Sergeevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2478638C1 |
| ETHYL 1,6-DIARYL-4-AROYL-3-HYDROXY-2-OXO-8-PHENYL-1,7-DIAZASPIRO[4,4]NONA-3,6,8-TRIEN-9-CARBOXILATES AND METHOD OF THEIR OBTAINING |
2011 |
- Silajchev Pavel Sergeevich
- Makhmudov Ramiz Ragibovich
- Maslivets Andrej Nikolaevich
|
RU2467010C1 |
| 1'-ARYL-4'-HYDROXY-3'-CYNNAMOYL-2H,4H-SPIRO[FURO[3,2-c]CHROMEN-3,2'-PYRROL]-2,4,5'(1'H)-TRIONES EXHIBITING ANALGESIC ACTIVITY, AND METHOD FOR PRODUCING THEM |
2014 |
- Silajchev Pavel Sergeevich
- Filimonov Valerij Olegovich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
|
RU2577523C2 |
| (3Z)-4-ARYL-HYDROXY-1-(1,3,3-TRIMETHYLINDOLIN-2-YLIDENE)BUT-3-EN-2-ONES AND SYNTHESIS METHOD THEREOF |
2009 |
- Konovalova Valerija Vladislavovna
- Maslivets Andrej Nikolaevich
|
RU2417219C1 |
