BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAID DERIVATIVES, PRODUCTION AND USE THEREOF Russian patent published in 2009 - IPC C07D235/14 A61K31/4184 A61P1/00 A61P25/00 A61P25/16 A61P25/22 A61P25/28 A61P35/00 A61P9/00 

Abstract RU 2374234 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to a compound of formula: which is N-{2-tert-butyl-1-[(4,4-diflurocyclohexyl)methyl]-1H-benzimidazol-5-yl}ethanesulfonamide and its pharmaceutically acceptable salt, their diastereomers, enantiomers or their mixture. The invention also relates to use of this compound in making a medicinal agent with modulator activity of CB1 receptors; to a pharmaceutical composition based on this compound; to a method of modulating CB1 receptors, based on use of effective quantities of this compound, as well as to a method of producing the compound described above.

EFFECT: obtaining a new derivative of benzimidazole with useful biological activity.

8 cl, 1 tbl, 28 ex

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RU 2 374 234 C2

Authors

Pazhe Daniel'

Liu Ziping

Trembleh Maksim

Uolpol Kristofer

Jang Khua

Dates

2009-11-27Published

2005-09-22Filed