FIELD: chemistry.
SUBSTANCE: oral administration form contains at least one type of probiotic microorganisms and a coating which includes at least two cellulose esters, preferably hydroxypropylmethylcellulose and hydroxyproylcellulose. One of the esters exclusively contains hydroxyalkyl groups as ester substitutes, and the second contains alkyl groups as ester substitutes, besides hydroxyalkyl groups. The said coating is prepared in an aqueous solution or in a water-alcohol solution.
EFFECT: provision for high activity of probiotic microorganisms in the intestines, as well as longer shelf-life of the form.
11 cl, 8 ex
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Authors
Dates
2009-12-20—Published
2005-05-04—Filed