COPOLYMERS OF N-VINYL AMIDES WITH UNSATURATED SORBOSE ESTERS Russian patent published in 2010 - IPC C08F226/06 C08F226/10 A61P37/04 A61K31/79 

Abstract RU 2381239 C1

FIELD: chemistry.

SUBSTANCE: invention relates to the chemistry of high-molecular compounds, specifically to copolymers of N-vinyl amides. According to the invention, the copolymer is characterised by general formula An-Bm, where A is an N-vinyl amide residue, B is a vinyl saccharide residue, and where n=100-m mol %; m=10.0-35.0 mol %. The vinyl saccharide residue used is (meth)acryloyl-sorbose, crotonoyl-sorbose. The N-vinyl amide residues used are N-vinyl formamide, N-vinyl pyrrolidone, N-methylvinyl amide. The copolymers are obtained in the presence of a radical initiator - dinitrile of azo-isobutyric acid, and then hydrolysed in aqueous solution of formic acid.

EFFECT: water-soluble copolymers in accordance with the invention have low-toxicity and high level of immuno-stimulating activity.

1 cl, 10 ex, 2 tbl

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RU 2 381 239 C1

Authors

Panarin Evgenij Fedorovich

Ivanova Nadezhda Petrovna

Zhuravskaja Ol'Ga Nikolaevna

Nesterova Natal'Ja Aleksandrovna

Belokhvostova Aleksandra Timofeevna

Potapenkova Ljubov' Sergeevna

Dates

2010-02-10Published

2008-07-11Filed