METHOD OF PREDICTING RISK OF BRONCHIAL ASTHMA DEVELOPMENT Russian patent published in 2010 - IPC G01N33/48 

Abstract RU 2383019 C1

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to pulmonology and allergology. Claimed is method of predicting risk of bronchial asthma developmenyt by means of prognostic model, based on data of genotyping taking into account opisthorchiasis invasion in regions endemic on helminth invasion. Polymorphic variants of genes SOCS7(rs3890580), PIASX (rs9304337) are determined in person's blood, additionally fact of presence/absence of opisthorchiasis is taken into account and probability of relating an individual to group with low risk of developing bronchial asthma or to group with high risk of developing bronchial asthma. Accuracy of prediction on the basis of claimed method constitutes 64-75%.

EFFECT: increase of determination accuracy.

1 ex, 4 tbl

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Authors

Ogorodova Ljudmila Mikhajlovna

Frejdin Maksim Borisovich

Cherevko Natal'Ja Anatol'Evna

Vasil'Eva Marija Vladimirovna

Bragina Elena Jur'Evna

Saltykova Irina Vladimirovna

Dates

2010-02-27Published

2008-12-09Filed