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2 383 536

(13)

(51)

IPC

C07D249/12(2006-01-01)

C07D401/12(2006-01-01)

C07D401/14(2006-01-01)

C07D405/12(2006-01-01)

A61K31/4196(2006-01-01)

A61K31/454(2006-01-01)

A61P1/04(2006-01-01)

A61P9/10(2006-01-01)

(21) (22)

Application

2007107940/04, 2005-08-04

(24)

Start date

2005-08-04

(22)

Actual filing date

2005-08-04

(45)

Published

2010-03-10

(72)

Inventor

Ono NaojaSato MasakazuSiozava FumijasuJagi MakotoJabuuti TetsujaTakajama TetsuoKatakai Khironori

(73)

Holder

Tajso Farmas'Jutikal Ko., Ltd.

TRIAZOLE DERIVATIVE Russian patent published in 2010 - IPC C07D249/12 C07D401/12 C07D401/14 C07D405/12 A61K31/4196 A61K31/454 A61P1/04 A61P9/10

Abstract RU 2383536 C2

FIELD: chemistry.

SUBSTANCE: described are novel triazole derivatives with general formula where values of radicals are given in the formula of invention, a pharmaceutical composition containing said derivatives, and a method of treating autoimmune diseases. Compounds with general formula (1) and their pharmaceutically acceptable salts have inhibition effect on S1P and its Edg-1 receptor (S1P1).

EFFECT: possibility of use as a pharmaceutical product.

43 cl, 10 ex, 1 tbl

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RU 2 383 536 C2

Authors

Ono Naoja

Sato Masakazu

Siozava Fumijasu

Jagi Makoto

Jabuuti Tetsuja

Takajama Tetsuo

Katakai Khironori

Dates

2010-03-10—Published

2005-08-04—Filed